SCHEMBL20161764

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18166590	0.94	CYP1A2 (0.69)	CYP1A2CYP3A4ALDH1A1LMNAGAA
	SCHEMBL18166647	0.92	CYP1A2 (0.66)	CYP1A2CYP3A4ALDH1A1LMNAGAA
	SCHEMBL18166663	0.91	CYP1A2 (0.71)	CYP1A2CYP3A4LMNAGAAMAPK1
	SCHEMBL1060801	0.90	CYP1A2 (0.72)	CYP1A2CYP3A4LMNAGAAMAPK1
	SCHEMBL18166736	0.90	CYP1A2 (0.72)	CYP1A2CYP3A4ALDH1A1LMNAGAA
	SCHEMBL1066761	0.89	CYP1A2 (0.71)	CYP1A2CYP3A4LMNAGAAMAPK1
	SCHEMBL18166737	0.89	CYP1A2 (0.71)	CYP1A2CYP3A4ALDH1A1LMNAGAA
	SCHEMBL18166730	0.89	PDE4A (0.62)	CYP1A2CYP3A4ALDH1A1LMNAGAA
	SCHEMBL1060574	0.89	CYP1A2 (0.70)	CYP1A2CYP3A4LMNAGAAMAPK1
	SCHEMBL18166555	0.89	CYP1A2 (0.70)	CYP1A2CYP3A4LMNAGAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.