Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 19/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.56 |
| ▸ | CTSK | P43235 | 4/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30195065 | 1.00 | CTSC (0.56) | CTSCKCNH2CTSKCTSSLTB4R | |
| SCHEMBL2074655 | 0.89 | CTSC (0.57) | CTSCKCNH2CTSKCTSS | |
| SCHEMBL2074657 | 0.89 | CTSC (0.57) | CTSCKCNH2CTSKCTSS | |
| SCHEMBL16485759 | 0.86 | CTSC (0.48) | CTSCKCNH2CTSKCTSSLTB4R | |
| SCHEMBL21013700 | 0.85 | CTSK (0.52) | CTSCCTSKCTSS | |
| SCHEMBL16478082 | 0.84 | CTSC (0.61) | CTSCKCNH2CTSKLTB4RLTB4R2 | |
| SCHEMBL16478084 | 0.84 | CTSC (0.61) | CTSCKCNH2CTSKLTB4RLTB4R2 | |
| SCHEMBL16485739 | 0.84 | CTSC (0.58) | CTSCKCNH2CTSKLTB4RLTB4R2 | |
| SCHEMBL16478098 | 0.84 | CTSC (0.63) | CTSCKCNH2CTSKLTB4RLTB4R2 | |
| SCHEMBL16478099 | 0.84 | CTSC (0.63) | CTSCKCNH2CTSKLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025351-A1 | CERTAIN (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS | BIOPHARMA CREDIT PLC (GB) | 2023-01-26 | — | — | US | disclosed |
| EP-3323814-A1 | (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE I INHIBITORS | AstraZeneca AB (SE) | 2018-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025351-A1 | CERTAIN (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS | DPP4, DPP7, DPEP1 | CTSC 7/4885KCNH2 2475/4885CTSK 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.