SCHEMBL20162162

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20162175	0.92	TAS2R8 (0.39)	TAS2R8WNT1GSK3BDYRK1ACLK2
	SCHEMBL20162174	0.90	HTR2C (0.43)	TAS2R8WNT1GSK3BDYRK1ACLK2
	SCHEMBL20162161	0.90	RIPK1 (0.40)	TAS2R8RIPK1PTGDR2
	SCHEMBL20162116	0.89	TAS2R8 (0.39)	TAS2R8CDK9WNT1GSK3BDYRK1A
	SCHEMBL20162131	0.88	TAS2R8 (0.46)	TAS2R8MAOBWNT1GSK3BDYRK1A
	SCHEMBL20162126	0.87	RIPK1 (0.39)	TAS2R8RIPK1
	SCHEMBL20162155	0.87	TAS2R8 (0.40)	TAS2R8CDK9WNT1GSK3BDYRK1A
	SCHEMBL20169996	0.86	HTR2C (0.46)	TAS2R8CDK9HTR2CHTR2BRIPK1
	SCHEMBL20162143	0.86	TAS2R8 (0.37)	TAS2R8CDK9WNT1GSK3BDYRK1A
	SCHEMBL20162150	0.86	HTR2C (0.46)	TAS2R8HTR2CHTR2BRIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.