Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | CES2 | O00748 | 6/20 | 0.35 |
| ▸ | CES1 | P23141 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20395699 | 1.00 | MEN1 (0.38) | MEN1ALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL20395664 | 0.96 | CYP3A4 (0.37) | MEN1ALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL20162235 | 0.96 | CYP3A4 (0.37) | MEN1ALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL20395679 | 0.94 | ALDH1A1 (0.39) | MEN1ALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL20395681 | 0.94 | ALDH1A1 (0.39) | MEN1ALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL20162281 | 0.90 | TOP2A (0.41) | MEN1ALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL20395689 | 0.90 | TOP2A (0.41) | MEN1ALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL20162237 | 0.89 | TDP1 (0.45) | MEN1ALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL20395700 | 0.87 | GAA (0.38) | MEN1ALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL20162251 | 0.87 | GAA (0.38) | MEN1ALDH1A1POLBKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| EP-3322400-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | LPO, CAT, GPX4 | MEN1 3221/4885ALDH1A1 1313/4885POLB 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.