Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367236 | 0.77 | IDO1 (0.51) | IDO1NR4A2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7888003 | 0.76 | IDO1 (0.69) | IDO1NR4A2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29984975 | 0.76 | IDO1 (0.69) | IDO1NR4A2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL165560 | 0.76 | IDO1 (0.69) | IDO1NR4A2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9367249 | 0.75 | IDO1 (0.49) | IDO1NR4A2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1989192 | 0.72 | IDO1 (0.64) | IDO1NR4A2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11157965 | 0.72 | IDO1 (0.64) | IDO1NR4A2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1989190 | 0.72 | IDO1 (0.64) | IDO1NR4A2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11129339 | 0.72 | IDO1 (0.64) | IDO1NR4A2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9767549 | 0.72 | IDO1 (1.00) | IDO1NR4A2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3322296-A1 | SUBSTITUTED OXO-TETRAHYDROQUINOLINYL-PHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-05-23 | — | — | EP | disclosed |