Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367249 | 0.87 | IDO1 (0.49) | IDO1MRGPRX4NR4A2L3MBTL1CYP1A2 | |
| SCHEMBL7888003 | 0.80 | IDO1 (0.69) | IDO1MRGPRX4NR4A2L3MBTL1CYP1A2 | |
| SCHEMBL20162387 | 0.77 | IDO1 (0.56) | IDO1MRGPRX4NR4A2L3MBTL1CYP1A2 | |
| SCHEMBL28649281 | 0.74 | IDO1 (0.62) | IDO1MRGPRX4NR4A2L3MBTL1CYP1A2 | |
| SCHEMBL3156683 | 0.73 | IDO1 (0.60) | IDO1MRGPRX4NR4A2L3MBTL1CYP1A2 | |
| SCHEMBL15677635 | 0.73 | IDO1 (0.60) | IDO1MRGPRX4NR4A2L3MBTL1CYP1A2 | |
| SCHEMBL165560 | 0.72 | IDO1 (0.69) | IDO1MRGPRX4NR4A2L3MBTL1CYP1A2 | |
| SCHEMBL29984975 | 0.72 | IDO1 (0.69) | IDO1MRGPRX4NR4A2L3MBTL1CYP1A2 | |
| SCHEMBL6857573 | 0.72 | IDO1 (0.58) | IDO1MRGPRX4NR4A2L3MBTL1CYP1A2 | |
| SCHEMBL28442446 | 0.71 | MRGPRX4 (0.57) | IDO1MRGPRX4NR4A2L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395174-B1 | Thiazole derivatives | SHELL INT RESEARCH (NL) | 1994-12-07 | — | — | EP | disclosed |
| US-5089512-A | Fungicides | SHELL RESEARCH LIMITED (GB) | 1992-02-18 | — | — | US | disclosed |
| EP-0395174-A2 | Thiazole derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-10-31 | — | — | EP | disclosed |