Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | PTAFR | P25105 | 3/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.56 |
| ▸ | FES | P07332 | 1/20 | 0.56 |
| ▸ | RET | P07949 | 1/20 | 0.56 |
| ▸ | MARK3 | P27448 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | FLT4 | P35916 | 1/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | CLK2 | P49760 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11006572 | 0.94 | FES (0.61) | PTAFRTBXAS1FESRETMARK3 | |
| SCHEMBL48869 | 0.90 | POLB (0.60) | TBXAS1FESRETMARK3TYK2 | |
| SCHEMBL2841099 | 0.86 | EPHX2 (0.65) | EPHX2PTAFRTBXAS1FESRET | |
| SCHEMBL2843163 | 0.81 | PTAFR (0.67) | EPHX2PTAFRTBXAS1FESRET | |
| SCHEMBL14276919 | 0.80 | CHRNB2 (0.54) | FESRETMARK3TYK2FLT4 | |
| SCHEMBL4603002 | 0.80 | CYP3A4 (0.69) | EPHX2PTAFRTBXAS1FESRET | |
| SCHEMBL29357760 | 0.80 | CYP3A4 (0.69) | EPHX2PTAFRTBXAS1FESRET | |
| SCHEMBL7165228 | 0.80 | TBXAS1 (0.68) | TBXAS1TDP1L3MBTL1 | |
| SCHEMBL45843 | 0.80 | RECQL (0.70) | FESRETMARK3TYK2FLT4 | |
| SCHEMBL422827 | 0.80 | L3MBTL1 (0.68) | EPHX2POLBL3MBTL1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091598-A2 | TREATMENT OF NEURODEGENERATIVE DISEASES | ICM (INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE) (FR) | 2018-05-24 | — | — | WO | disclosed |
| EP-3323415-A1 | TREATMENT OF NEURODEGENERATIVE DISEASES | Institut du Cerveau et de la Moelle Epiniere-ICM (FR) | 2018-05-23 | — | — | EP | disclosed |