Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162489 | 0.89 | TSHR (0.45) | TSHRALDH1A1HPGDLMNAATM | |
| SCHEMBL20162487 | 0.89 | TSHR (0.45) | TSHRALDH1A1HPGDLMNAATM | |
| SCHEMBL375032 | 0.88 | TSHR (0.57) | TSHRALDH1A1HPGDLMNAATM | |
| SCHEMBL666917 | 0.84 | TSHR (0.40) | TSHRALDH1A1LMNAHCAR2SMN1; SMN2 | |
| Isobutane SCHEMBL28165880 | 0.83 | TSHR (0.62) | TSHRALDH1A1LMNANAAAHCAR2 | |
| SCHEMBL374970 | 0.82 | TSHR (0.66) | TSHRALDH1A1HPGDLMNAATM | |
| SCHEMBL4578697 | 0.82 | ALDH1A1 (0.50) | TSHRALDH1A1HPGDLMNAATM | |
| SCHEMBL9488348 | 0.81 | TSHR (0.66) | TSHRALDH1A1HPGDLMNAATM | |
| SCHEMBL11850141 | 0.81 | TSHR (0.70) | TSHRALDH1A1LMNANAAAHCAR2 | |
| SCHEMBL11803516 | 0.80 | TSHR (0.69) | TSHRALDH1A1LMNANAAAHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396355-B1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN INC (US) | 2018-05-23 | — | — | EP | disclosed |