SCHEMBL666917

SCHEMBL666917

C=C(CC)C(=O)OC(C)C

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
LMNA P02545 2/20 0.38
ADRA1A P35348 1/20 0.36
PDE4D Q08499 1/20 0.36
XPO1 O14980 3/20 0.35
HCAR2 Q8TDS4 1/20 0.32
GAA P10253 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2799572 0.84 TSHR (0.34) TSHR
SCHEMBL9746345 0.84 TSHR (0.39) TSHRLMNAADRA1APDE4DXPO1
SCHEMBL20162488 0.84 TSHR (0.46) TSHRLMNAHCAR2SMN1; SMN2ALDH1A1
SCHEMBL8621634 0.83 TSHR (0.32) TSHRALDH1A1
SCHEMBL3476792 0.82 LMNA (0.44) TSHRLMNAADRA1APDE4DXPO1
SCHEMBL6014318 0.82 TSHR (0.33) TSHR
SCHEMBL6612206 0.82 TSHR (0.33) TSHR
SCHEMBL26129905 0.81 TSHR (0.40) TSHRLMNAADRA1APDE4DXPO1
SCHEMBL640114 0.81 TSHR (0.40) TSHRLMNAADRA1APDE4DXPO1
SCHEMBL16659456 0.80 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114727521-A Shell assembly and electronic equipment OPPO广东移动通信有限公司 2022-07-08 CN claimed
CN-101405304-A Method for producing polymers in aqueous solvents BASF SE (DE) 2009-04-08 CN claimed
CN-101282706-A Copolymers for cosmetic applications BASF SE (DE) 2008-10-08 CN claimed
EP-4326703-A1 MONOMERIC AND POLYMERIC COMPOSITIONS AND METHODS OF PRODUCING AND USING THE SAME Align Technology, Inc. (US) 2024-02-28 EP disclosed
US-11879063-B2 Binder compositions and uses thereof KNAUF INSULATION, INC. 2024-01-23 US disclosed
CN-117192671-A Polarizing plate with phase difference layer 日东电工株式会社 2023-12-08 CN disclosed
CN-117192672-A Resin film, method for producing resin film, and method for producing phase difference film 日东电工株式会社 2023-12-08 CN disclosed
US-20230331956-A1 SULFIDE-CONTAINING STABILIZER SYSTEM FOR THIOL-ENE AND THIOL-YNE COMPOSITIONS BRUNO BOCK CHEMISCHE FABRIK GMBH & CO. KG (DE) 2023-10-19 US disclosed
WO-2023190750-A1 POLYMER FILM-FORMING COMPOSITION AND SELECTIVE POLYMER FILM-FORMING METHOD 日産化学株式会社 2023-10-05 WO disclosed
EP-4214277-A1 SULFIDE-CONTAINING STABILIZER SYSTEM FOR THIOL-ENE AND THIOL-YNE COMPOSITIONS Bruno Bock GmbH (DE) 2023-07-26 EP disclosed
CN-112771112-B Aqueous composition 陶氏环球技术有限责任公司 2023-03-21 CN disclosed
US-20060223848-A1 Caspase inhibitors containing isoxazoline ring LG CHEM, LTD. (KR) 2006-10-05 US disclosed
EP-1660464-A1 CASPASE INHIBITORS CONTAINING ISOXAZOLINE RING LG Life Sciences Ltd. (KR) 2006-05-31 EP disclosed
WO-2005021516-A1 CASPASE INHIBITORS CONTAINING ISOXAZOLINE RING LG LIFE SCIENCES LTD. (KR) 2005-03-10 WO disclosed
EP-1212309-B1 CASPASE INHIBITOR LG CHEM INVESTMENT LTD (KR) 2004-08-18 EP disclosed
US-6747050-B1 INHIBITING THE ACTIVITY OF CASPASES, PREVENTING INFLAMMATION AND APOPTOSIS LG CHEM INVESTMENT LTD. (KR) 2004-06-08 US disclosed
EP-1212309-A4 CASPASE INHIBITOR LG CHEM INVESTMENT LTD (KR) 2002-11-27 EP disclosed
EP-1212309-A1 CASPASE INHIBITOR LG Chem Investment, Ltd. (KR) 2002-06-12 EP disclosed
WO-2001021600-A1 CASPASE INHIBITOR LG CHEM INVESTMENT LTD. (KR) 2001-03-29 WO disclosed
US-5100762-A Radiation-sensitive polymer and radiation-sensitive composition containing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223848-A1 Caspase inhibitors containing isoxazoline ring CASP1, CASP7, CASP2 TSHR 4742/4885LMNA 366/4885ADRA1A 3926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.