Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162487 | 0.94 | TSHR (0.45) | TSHRLMNAALDH1A1HPGDATM | |
| SCHEMBL3477585 | 0.90 | LMNA (0.50) | TSHRLMNAALDH1A1MAPTCES2 | |
| SCHEMBL20162488 | 0.89 | TSHR (0.46) | TSHRLMNAALDH1A1HPGDATM | |
| SCHEMBL3081526 | 0.88 | TSHR (0.55) | TSHRLMNAALDH1A1HPGDATM | |
| Ethylene SCHEMBL27507038 | 0.86 | TSHR (0.53) | TSHRLMNAALDH1A1HPGDATM | |
| SCHEMBL29168696 | 0.86 | TSHR (0.53) | TSHRLMNAALDH1A1HPGDATM | |
| SCHEMBL29117791 | 0.84 | LMNA (0.58) | TSHRLMNAALDH1A1MAPTTDP1 | |
| SCHEMBL5167857 | 0.84 | TSHR (0.60) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL11171251 | 0.83 | LMNA (0.61) | TSHRLMNAALDH1A1MAPTTDP1 | |
| SCHEMBL15610760 | 0.83 | LMNA (0.61) | TSHRLMNAALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396355-B1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN INC (US) | 2018-05-23 | — | — | EP | disclosed |