SCHEMBL3477585

SCHEMBL3477585

C=C(CCCC)C(=O)OC(C)C

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
CES1 P23141 3/20 0.39
CES2 O00748 2/20 0.39
ALDH1A1 P00352 2/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 4/20 0.36
CA1 P00915 1/20 0.35
MAPT P10636 2/20 0.35
MAPK1 P28482 2/20 0.35
ALOX15 P16050 1/20 0.33
MEN1 O00255 1/20 0.33
FAAH O00519 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29117791 0.94 LMNA (0.58) LMNACES1CES2ALDH1A1TSHR
SCHEMBL29096239 0.92 LMNA (0.61) LMNACES1CES2ALDH1A1TSHR
SCHEMBL29177465 0.92 LMNA (0.61) LMNACES1CES2ALDH1A1TSHR
SCHEMBL11171251 0.92 LMNA (0.61) LMNACES1CES2ALDH1A1TSHR
SCHEMBL15610760 0.92 LMNA (0.61) LMNACES1CES2ALDH1A1TSHR
SCHEMBL20162489 0.90 TSHR (0.45) LMNACES1CES2ALDH1A1TSHR
SCHEMBL3476792 0.88 LMNA (0.44) LMNACES1CES2ALDH1A1TSHR
SCHEMBL27822863 0.86 LMNA (0.40) LMNACES1CES2ALDH1A1TP53
SCHEMBL28658332 0.85 LMNA (0.39) LMNACES1CES2ALDH1A1TP53
SCHEMBL28299794 0.84 CES1 (0.39) LMNACES1CES2ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110194937-B Double-sided pressure-sensitive adhesive tape 日东电工株式会社 2022-04-15 CN disclosed
US-8680172-B2 Copolymers for intraocular lens systems VISIOGEN, INC. (US) 2014-03-25 US disclosed
US-20130245756-A1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS LILLY MING INTERNATIONAL, INC. 2013-09-19 US disclosed
US-8430928-B2 Copolymers for intraocular lens systems VISIOGEN, INC. (US) 2013-04-30 US disclosed
US-20120245684-A1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS VISIOGEN, INC. (US) 2012-09-27 US disclosed
US-8222360-B2 Copolymers for intraocular lens systems VISIOGEN, INC. (US) 2012-07-17 US disclosed
US-20100211170-A1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS VISIOGEN, INC. (US) 2010-08-19 US disclosed
WO-2010093823-A2 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS VISIOGEN, INC. (US) 2010-08-19 WO disclosed
US-20030019813-A1 Antimicrobial polymer foams with amino alcohols DE GUSSA AG (DE) 2003-01-30 US disclosed