Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17786771 | 1.00 | TSHR (0.39) | TSHRALDH1A1LMNACETPNPC1 | |
| SCHEMBL7771446 | 0.88 | FDPS (0.39) | LMNA | |
| SCHEMBL7795340 | 0.86 | SMN1; SMN2 (0.38) | TSHRALDH1A1LMNANPC1RAB9A | |
| SCHEMBL20856173 | 0.86 | SMN1; SMN2 (0.38) | TSHRALDH1A1LMNANPC1RAB9A | |
| SCHEMBL472178 | 0.81 | ALDH1A1 (0.38) | TSHRALDH1A1LMNACETPKDM4E | |
| SCHEMBL779563 | 0.81 | SMN1; SMN2 (0.37) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7025600 | 0.79 | CHRM2 (0.38) | ALDH1A1NPC1RAB9APAX8SMN1; SMN2 | |
| SCHEMBL7028386 | 0.79 | PTGIR (0.39) | — | |
| SCHEMBL22321965 | 0.79 | KDM4E (0.36) | TSHRALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL382026 | 0.79 | KDM4E (0.36) | TSHRALDH1A1LMNASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928475-B1 | ANTIVIRAL PHOSPHORAMIDATES OF 4'-C-AZIDO-SUBSTITUTED PRONUCLEOTIDES | RIBOSCIENCE LLC (US) | 2018-05-23 | — | — | EP | disclosed |