Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18953880 | 0.75 | — | — | |
| SCHEMBL28520734 | 0.73 | TRPA1 (0.33) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL2016294 | 0.72 | ALDH1A1 (0.39) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL12913453 | 0.69 | MMP13 (0.46) | SLC6A2MMP12MMP13ALDH1A1 | |
| SCHEMBL7252952 | 0.68 | EPHX1 (0.55) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL3818361 | 0.68 | CPA1 (0.60) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL6462362 | 0.68 | CPA1 (0.60) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL4178375 | 0.67 | MAPT (0.49) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Dl-Phenylalanine SCHEMBL8610372 | 0.66 | SLC7A5 (0.79) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL11205464 | 0.66 | NPC1 (0.47) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073845-A1 | N-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-06-23 | — | — | WO | disclosed |