SCHEMBL20163171

SCHEMBL20163171

COC(=O)C(=Cc1ccco1)C(=O)OC

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.67
KMT2A Q03164 4/20 0.54
TDP1 Q9NUW8 3/20 0.54
MEN1 O00255 3/20 0.54
POLB P06746 2/20 0.54
KDM4E B2RXH2 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ALDH1A1 P00352 2/20 0.52
GAA P10253 2/20 0.52
TSHR P16473 1/20 0.51
CYP2C19 P33261 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9401906 0.92 MAPT (0.61) MAPTKMT2ATDP1MEN1POLB
SCHEMBL20176812 0.92 MAPT (0.61) MAPTKMT2ATDP1MEN1POLB
SCHEMBL9401911 0.92 MAPT (0.61) MAPTKMT2ATDP1MEN1POLB
SCHEMBL20726617 0.85 MAPT (0.51) MAPTKMT2ATDP1MEN1POLB
SCHEMBL17439333 0.84 MAPT (0.56) MAPTKMT2ATDP1MEN1POLB
SCHEMBL17439335 0.84 MAPT (0.56) MAPTKMT2ATDP1MEN1POLB
SCHEMBL11781592 0.81 POLB (0.68) MAPTKMT2ATDP1MEN1POLB
SCHEMBL9316158 0.79 MAPT (0.63) MAPTKMT2ATDP1MEN1POLB
SCHEMBL1176560 0.79 POLB (0.72) MAPTKMT2ATDP1MEN1POLB
SCHEMBL1176559 0.79 POLB (0.72) MAPTKMT2ATDP1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180140525-A1 AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES HENKEL AG & CO. KGAA (DE) 2018-05-24 US claimed
US-20250051687-A1 MALONATE AND FURAN BASED SURFACTANTS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2025-02-13 US disclosed
EP-4433465-A1 MALONATE AND FURAN BASED SURFACTANTS Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO (NL) 2024-09-25 EP disclosed
WO-2023091017-A1 MALONATE AND FURAN BASED SURFACTANTS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2023-05-25 WO disclosed
EP-4183779-A1 MALONATE AND FURAN BASED SURFACTANTS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2023-05-24 EP disclosed
CN-107602372-B Process for producing fatty acid 中国科学技术大学 2020-08-25 CN disclosed
US-10561594-B2 Agent for stabilizing keratin fibers with 5-ring heterocycles HENKEL AG & CO. KGAA (DE) 2020-02-18 US disclosed
US-10561594-B2 Agent for stabilizing keratin fibers with 5-ring heterocycles HENKEL AG & CO. KGAA (DE) 2020-02-18 US disclosed
US-20180140525-A1 AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES HENKEL AG & CO. KGAA (DE) 2018-05-24 US disclosed
US-20180140525-A1 AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES HENKEL AG & CO. KGAA (DE) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180140525-A1 AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES KRT18, NDUFS5, NDUFA5 MAPT 1624/4885KMT2A 2242/4885TDP1 4143/4885
US-10561594-B2 Agent for stabilizing keratin fibers with 5-ring heterocycles KRT18, NDUFS5, NDUFA5 MAPT 1624/4885KMT2A 2242/4885TDP1 4143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.