Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401911 | 1.00 | MAPT (0.61) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL9401906 | 1.00 | MAPT (0.61) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL20163171 | 0.92 | MAPT (0.67) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL9316158 | 0.86 | MAPT (0.63) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL17439333 | 0.83 | MAPT (0.56) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL17439335 | 0.83 | MAPT (0.56) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL10377521 | 0.83 | TDP1 (0.63) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL11690331 | 0.83 | TDP1 (0.63) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL20176814 | 0.83 | TDP1 (0.63) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL27465110 | 0.81 | MAPT (0.71) | MAPTTDP1POLBKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180140525-A1 | AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180140525-A1 | AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES | KRT18, NDUFS5, NDUFA5 | MAPT 1624/4885TDP1 4143/4885POLB 1895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.