Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401911 | 1.00 | MAPT (0.61) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL20176812 | 1.00 | MAPT (0.61) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL20163171 | 0.92 | MAPT (0.67) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL9316158 | 0.86 | MAPT (0.63) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL17439333 | 0.83 | MAPT (0.56) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL17439335 | 0.83 | MAPT (0.56) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL10377521 | 0.83 | TDP1 (0.63) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL11690331 | 0.83 | TDP1 (0.63) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL20176814 | 0.83 | TDP1 (0.63) | MAPTTDP1POLBKDM4EL3MBTL1 | |
| SCHEMBL27465110 | 0.81 | MAPT (0.71) | MAPTTDP1POLBKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |