Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29117671 | 0.85 | ELANE (0.45) | ELANEMAPTALDH1A1CYP1A2RECQL | |
| SCHEMBL28856142 | 0.82 | ELANE (0.50) | ELANEMAPTALDH1A1L3MBTL1TDP1 | |
| SCHEMBL28144760 | 0.82 | ELANE (0.42) | ELANEMAPTALDH1A1CYP1A2GAA | |
| SCHEMBL7688111 | 0.81 | ELANE (0.47) | ELANEMAPTALDH1A1HSP90AA1GAA | |
| SCHEMBL237447 | 0.79 | CES2 (0.50) | ELANEMAPTALDH1A1RECQLATM | |
| SCHEMBL20174131 | 0.78 | ELANE (0.45) | ELANEMAPTALDH1A1HSP90AA1GAA | |
| SCHEMBL27546729 | 0.78 | ELANE (0.45) | ELANEMAPTALDH1A1HSP90AA1GAA | |
| SCHEMBL14717313 | 0.78 | ELANE (0.45) | ELANEMAPTALDH1A1HSP90AA1GAA | |
| SCHEMBL372385 | 0.78 | ELANE (0.45) | ELANEMAPTALDH1A1HSP90AA1GAA | |
| Diphenyl Ethanedioat SCHEMBL27942895 | 0.78 | ELANE (0.53) | ELANEMAPTALDH1A1CYP1A2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10251826-B2 | Alkaline agent for lightening hair containing oxidants and special carboxylic acid esters | HENKEL AG & CO. KGAA (DE) | 2019-04-09 | — | — | US | claimed |
| US-20180140523-A1 | ALKALINE AGENT FOR LIGHTENING HAIR CONTAINING OXIDANTS AND SPECIAL CARBOXYLIC ACID ESTERS | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | claimed |
| US-10251826-B2 | Alkaline agent for lightening hair containing oxidants and special carboxylic acid esters | HENKEL AG & CO. KGAA (DE) | 2019-04-09 | — | — | US | disclosed |
| US-10251826-B2 | Alkaline agent for lightening hair containing oxidants and special carboxylic acid esters | HENKEL AG & CO. KGAA (DE) | 2019-04-09 | — | — | US | disclosed |
| US-20180140523-A1 | ALKALINE AGENT FOR LIGHTENING HAIR CONTAINING OXIDANTS AND SPECIAL CARBOXYLIC ACID ESTERS | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20180140523-A1 | ALKALINE AGENT FOR LIGHTENING HAIR CONTAINING OXIDANTS AND SPECIAL CARBOXYLIC ACID ESTERS | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20180140523-A1 | ALKALINE AGENT FOR LIGHTENING HAIR CONTAINING OXIDANTS AND SPECIAL CARBOXYLIC ACID ESTERS | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10251826-B2 | Alkaline agent for lightening hair containing oxidants and special carboxylic acid esters | KRT18, ALDH7A1, ALDH1A2 | ELANE 1509/4885MAPT 1367/4885ALDH1A1 14/4885 |
| US-20180140523-A1 | ALKALINE AGENT FOR LIGHTENING HAIR CONTAINING OXIDANTS AND SPECIAL CARBOXYLIC ACID ESTERS | KRT18, ALDH7A1, ALDH1A2 | ELANE 1509/4885MAPT 1367/4885ALDH1A1 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.