Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249461 | 0.89 | KMT2A (0.45) | KMT2AMEN1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL20164285 | 0.88 | TP53 (0.44) | KMT2AMEN1ALDH1A1TP53TRPV1 | |
| SCHEMBL18249398 | 0.88 | GAA (0.40) | KMT2AMEN1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL20164292 | 0.87 | THRB (0.38) | KMT2AALDH1A1SMN1; SMN2GAATSHR | |
| SCHEMBL18249469 | 0.86 | KMT2A (0.41) | KMT2AMEN1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL20164247 | 0.84 | KMT2A (0.45) | KMT2AMEN1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL18249379 | 0.83 | KMT2A (0.39) | KMT2AMEN1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL18249419 | 0.81 | KDM4E (0.48) | KMT2AMEN1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL18249388 | 0.79 | LMNA (0.42) | KMT2AMEN1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL10824225 | 0.79 | KMT2A (0.47) | KMT2AMEN1ALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |