Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 3/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164271 | 0.91 | ALDH1A1 (0.60) | ALDH1A1HPGDSMN1; SMN2KMT2ANOD2 | |
| SCHEMBL20164224 | 0.88 | ALDH1A1 (0.55) | ALDH1A1HPGDSMN1; SMN2KMT2ALMNA | |
| SCHEMBL20164212 | 0.87 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2KMT2ANOD2 | |
| SCHEMBL18249416 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDSMN1; SMN2KMT2ALMNA | |
| SCHEMBL20164233 | 0.80 | KMT2A (0.49) | ALDH1A1HPGDSMN1; SMN2KMT2ALMNA | |
| SCHEMBL18249405 | 0.79 | KMT2A (0.67) | ALDH1A1HPGDSMN1; SMN2KMT2ALMNA | |
| SCHEMBL20164258 | 0.77 | KMT2A (0.43) | ALDH1A1SMN1; SMN2KMT2ANOD2LMNA | |
| SCHEMBL20164252 | 0.76 | KMT2A (0.51) | ALDH1A1HPGDSMN1; SMN2KMT2ALMNA | |
| SCHEMBL18249474 | 0.76 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2KMT2ALMNANPSR1 | |
| SCHEMBL10447849 | 0.74 | ALDH1A1 (0.71) | ALDH1A1HPGDSMN1; SMN2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |