Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | SCN1A | P35498 | 2/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164277 | 0.91 | LMNA (0.58) | TDP1LMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL15933417 | 0.87 | TDP1 (0.64) | TDP1LMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL20164210 | 0.86 | GAA (0.70) | LMNAALDH1A1SMN1; SMN2GAACYP1A2 | |
| SCHEMBL20164297 | 0.84 | GAA (0.50) | LMNAALDH1A1SMN1; SMN2GAACYP1A2 | |
| SCHEMBL20164216 | 0.84 | ALDH1A1 (0.52) | TDP1LMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL1067976 | 0.83 | TDP1 (0.55) | TDP1LMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL11287086 | 0.82 | GAA (0.71) | TDP1LMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6415229 | 0.80 | TDP1 (0.58) | TDP1LMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL28646633 | 0.79 | TDP1 (0.53) | TDP1LMNAALDH1A1SMN1; SMN2GAA | |
| Ethyl Benzoate SCHEMBL21531031 | 0.78 | LMNA (0.63) | TDP1LMNAALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |