Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | SCN1A | P35498 | 3/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164227 | 0.92 | ALDH1A1 (0.49) | ALDH1A1LMNACYP1A2SCN1ASCN2A | |
| SCHEMBL20164210 | 0.84 | GAA (0.70) | ALDH1A1LMNACYP1A2SCN1ASCN2A | |
| SCHEMBL20164205 | 0.84 | TDP1 (0.58) | ALDH1A1LMNACYP1A2SCN1ASCN2A | |
| SCHEMBL18249406 | 0.82 | TSHR (0.42) | ALDH1A1LMNACYP3A4DRD3TSHR | |
| SCHEMBL10950553 | 0.80 | ESR1 (0.70) | ALDH1A1LMNACYP1A2SCN1ASCN2A | |
| SCHEMBL571227 | 0.79 | CA1 (0.63) | ALDH1A1LMNACYP1A2CYP3A4KCNH2 | |
| SCHEMBL20164298 | 0.78 | LMNA (0.41) | ALDH1A1LMNACYP1A2SCN1ASCN2A | |
| SCHEMBL16556222 | 0.77 | LMNA (0.50) | ALDH1A1LMNACYP1A2SCN1ASCN2A | |
| SCHEMBL10949603 | 0.77 | ALDH1A1 (0.68) | ALDH1A1LMNACYP1A2CYP2D6CYP3A4 | |
| SCHEMBL20164272 | 0.76 | MAPT (0.38) | ALDH1A1LMNACYP1A2GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |