Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249396 | 0.89 | LMNA (0.49) | ELANELMNATP53ALDH1A1MEN1 | |
| SCHEMBL18249462 | 0.88 | ELANE (0.40) | ELANELMNATP53CHRM2CHRM4 | |
| SCHEMBL20164234 | 0.86 | USP2 (0.44) | TP53ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL20164232 | 0.86 | LMNA (0.45) | LMNATP53ALDH1A1HRH1KCNH2 | |
| SCHEMBL15233921 | 0.81 | ELANE (0.44) | ELANELMNATP53CHRM2CHRM4 | |
| SCHEMBL1072030 | 0.80 | HPGD (0.50) | CHRM2CHRM4CHRM1CHRM3HPGD | |
| SCHEMBL30395772 | 0.80 | HPGD (0.50) | CHRM2CHRM4CHRM1CHRM3HPGD | |
| SCHEMBL18249470 | 0.78 | ALDH1A1 (0.50) | ELANELMNATP53CHRM2CHRM4 | |
| SCHEMBL18249403 | 0.78 | TSHR (0.42) | LMNATP53CHRM2CHRM4CHRM1 | |
| SCHEMBL18249401 | 0.77 | HPGD (0.47) | ELANELMNATP53CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |