Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164206 | 0.91 | MAPT (0.42) | NPSR1SMN1; SMN2MAPTTDP1L3MBTL1 | |
| SCHEMBL20164267 | 0.89 | TP53 (0.38) | NPSR1SMN1; SMN2MAPTTDP1L3MBTL1 | |
| SCHEMBL20164240 | 0.87 | NR1H4 (0.39) | NPSR1SMN1; SMN2MAPTTDP1L3MBTL1 | |
| SCHEMBL20164228 | 0.85 | ABCB1 (0.35) | NPSR1SMN1; SMN2MAPTL3MBTL1KMT2A | |
| SCHEMBL20164300 | 0.85 | ABCB1 (0.38) | NPSR1SMN1; SMN2MAPTL3MBTL1KMT2A | |
| SCHEMBL16556137 | 0.85 | NPSR1 (0.41) | NPSR1SMN1; SMN2ESR1ESR2MAPT | |
| SCHEMBL16556228 | 0.83 | NPSR1 (0.42) | NPSR1ESR1ESR2MAPTTDP1 | |
| SCHEMBL20164245 | 0.83 | LMNA (0.43) | NPSR1SMN1; SMN2MAPTTDP1L3MBTL1 | |
| SCHEMBL20164256 | 0.82 | ABCB1 (0.35) | NPSR1SMN1; SMN2MAPTL3MBTL1KMT2A | |
| SCHEMBL20164273 | 0.80 | MAPT (0.43) | NPSR1SMN1; SMN2MAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |