Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ESRRG | P62508 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164300 | 0.90 | ABCB1 (0.38) | ABCB1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL20164290 | 0.89 | RAB9A (0.35) | MAPTLMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL20164243 | 0.89 | MAPT (0.40) | MAPTLMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL20164228 | 0.86 | ABCB1 (0.35) | ABCB1TAS1R3TAS1R1MAPTLMNA | |
| SCHEMBL20164240 | 0.86 | NR1H4 (0.39) | ABCB1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL20164299 | 0.83 | LMNA (0.38) | MAPTLMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL20164239 | 0.82 | NPSR1 (0.38) | ABCB1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL20164288 | 0.81 | MAPT (0.34) | ABCB1TAS1R3TAS1R1MAPTLMNA | |
| SCHEMBL18249379 | 0.79 | KMT2A (0.39) | MAPTLMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL18249443 | 0.79 | ABCB1 (0.39) | ABCB1MAPTLMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |