Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | ACR | P10323 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249465 | 0.90 | KMT2A (0.45) | SMN1; SMN2NPSR1USP2HSD17B10MAPT | |
| SCHEMBL20164244 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2NPSR1USP2HSD17B10THRB | |
| SCHEMBL20164247 | 0.88 | KMT2A (0.45) | SMN1; SMN2NPSR1MAPTALDH1A1KMT2A | |
| SCHEMBL20164292 | 0.86 | THRB (0.38) | SMN1; SMN2NPSR1THRBMAPTALDH1A1 | |
| SCHEMBL20164275 | 0.82 | ABCB1 (0.40) | SMN1; SMN2NPSR1THRBMAPTALDH1A1 | |
| SCHEMBL20164248 | 0.80 | PTGS2 (0.42) | HSD17B10ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL20164208 | 0.80 | LMNA (0.47) | NPSR1USP2THRBMAPTALDH1A1 | |
| SCHEMBL20164262 | 0.79 | NR2F2 (0.36) | SMN1; SMN2NPSR1USP2HSD17B10THRB | |
| SCHEMBL18249443 | 0.79 | ABCB1 (0.39) | SMN1; SMN2THRBMAPTALDH1A1KMT2A | |
| SCHEMBL18249400 | 0.79 | KMT2A (0.44) | SMN1; SMN2NPSR1USP2HSD17B10THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |