Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164274 | 0.89 | KMT2A (0.51) | NCEH1KMT2AALDH1A1NOD2LMNA | |
| SCHEMBL20164258 | 0.87 | KMT2A (0.43) | NCEH1KMT2AALDH1A1NOD2LMNA | |
| SCHEMBL18249412 | 0.83 | MAPT (0.37) | KMT2AALDH1A1NOD2LMNASMN1; SMN2 | |
| SCHEMBL20164244 | 0.81 | SMN1; SMN2 (0.41) | KMT2AALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL20164251 | 0.80 | LMNA (0.46) | NCEH1KMT2AALDH1A1NOD2LMNA | |
| SCHEMBL20164262 | 0.80 | NR2F2 (0.36) | NCEH1KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL15536543 | 0.79 | ALDH1A1 (0.43) | KMT2AALDH1A1NOD2LMNASMN1; SMN2 | |
| SCHEMBL16236122 | 0.78 | KMT2A (0.43) | NCEH1KMT2AALDH1A1NOD2LMNA | |
| SCHEMBL20164212 | 0.78 | ALDH1A1 (0.53) | NCEH1KMT2AALDH1A1NOD2LMNA | |
| SCHEMBL18249415 | 0.78 | ABCB1 (0.37) | KMT2AALDH1A1NOD2SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |