Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 6/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16094375 | 0.82 | SLC29A1 (0.47) | KMT2ASLC29A1PDE10ANR1I2AHR | |
| SCHEMBL20164491 | 0.81 | SLC29A1 (0.46) | KMT2ASLC29A1CCNE2CDK4CCND1 | |
| SCHEMBL20164638 | 0.81 | SLC29A1 (0.54) | KMT2ASLC29A1PDE10AHTTNR1I2 | |
| Hydrochloric Acid SCHEMBL20164513 | 0.80 | SLC29A1 (0.44) | KMT2ASLC29A1CCNE2CDK4CCND1 | |
| SCHEMBL20164648 | 0.79 | KMT2A (0.43) | KMT2ASLC29A1PDE10ANR1I2AHR | |
| SCHEMBL20164645 | 0.78 | SLC29A1 (0.51) | KMT2ASLC29A1PDE10AHTTNR1I2 | |
| SCHEMBL20164668 | 0.76 | SLC29A1 (0.44) | KMT2ASLC29A1PDE10AHTTNR1I2 | |
| SCHEMBL20164779 | 0.76 | SLC29A1 (0.42) | KMT2ASLC29A1PDE10ANR1I2AHR | |
| SCHEMBL20164769 | 0.73 | SLC29A1 (0.42) | KMT2ASLC29A1PDE10AHTTNR1I2 | |
| SCHEMBL20164669 | 0.73 | SLC29A1 (0.42) | KMT2ASLC29A1PDE10AHTTNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3316890-B1 | NOVEL BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF MAKING AND USING SAME | NEURAD LTD (IL) | 2023-09-06 | — | — | EP | disclosed |
| US-10294228-B2 | Breathing control modulating compounds, and methods of making and using same | NEURAD LTD. (IL) | 2019-05-21 | — | — | US | disclosed |
| US-20180141953-A1 | Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same | NEURAD LTD. (IL) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141953-A1 | Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same | MTNR1B, CHRM3, PER2 | KMT2A 2456/4885SLC29A1 4472/4885PDE10A 154/4885 |
| US-10294228-B2 | Breathing control modulating compounds, and methods of making and using same | MTNR1B, PDE3A, CHRM3 | KMT2A 2528/4885SLC29A1 4518/4885PDE10A 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.