SCHEMBL20164491

SCHEMBL20164491

CCCNc1nc(NC)nc2c(NC(C)(C)CO)nc(NC)nc12

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 6/20 0.46
CCNE2 O96020 1/20 0.36
CDK4 P11802 1/20 0.36
CCND1 P24385 1/20 0.36
CCNE1 P24864 1/20 0.36
CDK2 P24941 1/20 0.36
KMT2A Q03164 2/20 0.34
TLR7 Q9NYK1 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MEN1 O00255 1/20 0.33
PDE4A P27815 2/20 0.32
BCDIN3D Q7Z5W3 1/20 0.30
APP P05067 1/20 0.30
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20164513 0.99 SLC29A1 (0.44) SLC29A1CCNE2CDK4CCND1CCNE1
SCHEMBL16094312 0.83 SLC29A1 (0.51) SLC29A1KMT2ATLR7MEN1PDE4A
SCHEMBL20164443 0.82 SLC29A1 (0.66) SLC29A1KMT2ATLR7MEN1APP
SCHEMBL20164626 0.81 KMT2A (0.44) SLC29A1CCNE2CDK4CCND1CCNE1
Hydrochloric Acid SCHEMBL17494536 0.81 SLC29A1 (0.50) SLC29A1KMT2ATLR7MEN1APP
SCHEMBL20179386 0.81 SLC29A1 (0.43) SLC29A1KMT2ATLR7PDE4A
Hydrochloric Acid SCHEMBL20164696 0.80 SLC29A1 (0.64) SLC29A1KMT2ATLR7MEN1APP
SCHEMBL20164475 0.79 SLC29A1 (0.44) SLC29A1CCNE1CDK2KMT2ATLR7
SCHEMBL20164523 0.79 SLC29A1 (0.62) SLC29A1CDK2KMT2ATLR7
SCHEMBL16094829 0.79 SLC29A1 (0.71) SLC29A1CCNE2CCNE1CDK2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US claimed
US-20250057848-A1 GAL475 COMPOSITIONS AND METHODS OF USE THEREOF NEURIM PHARMACEUTICALS (1991) LTD. (IL) 2025-02-20 US disclosed
EP-3316890-B1 NOVEL BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF MAKING AND USING SAME NEURAD LTD (IL) 2023-09-06 EP disclosed
EP-3316890-B1 NOVEL BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF MAKING AND USING SAME NEURAD LTD (IL) 2023-09-06 EP disclosed
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same NEURAD LTD. (IL) 2019-05-21 US disclosed
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same NEURAD LTD. (IL) 2019-05-21 US disclosed
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US disclosed
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same MTNR1B, CHRM3, PER2 SLC29A1 4472/4885CCNE2 3622/4885CDK4 4039/4885
US-20250057848-A1 GAL475 COMPOSITIONS AND METHODS OF USE THEREOF GPR119, GPR35, GPR55 SLC29A1 2077/4885CCNE2 4429/4885CDK4 4219/4885
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same MTNR1B, PDE3A, CHRM3 SLC29A1 4518/4885CCNE2 3731/4885CDK4 4220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.