Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017654 | 0.92 | HTT (0.61) | HPGDKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL771801 | 0.85 | KDM4E (0.57) | HPGDKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL771444 | 0.82 | HTT (0.59) | HPGDKDM4EALDH1A1HTTMEN1 | |
| SCHEMBL10440167 | 0.82 | NAAA (0.57) | HPGDALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL3754605 | 0.82 | NAAA (0.57) | HPGDALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL29322817 | 0.80 | HTT (0.65) | HPGDKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL18773534 | 0.80 | SMN1; SMN2 (0.60) | HPGDKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL17911673 | 0.80 | HTT (0.56) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL24849909 | 0.79 | HPGD (0.57) | HPGDKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL31245842 | 0.79 | HPGD (0.57) | HPGDKDM4EALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080016-A2 | METHODS OF DIRECTED SELF-ASSEMBLY AND LAYERED STRUCTURES FORMED THEREFROM | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011073013-A1 | METHODS OF DIRECTED SELF-ASSEMBLY WITH 193 - NM IMMERSION LITHOGRAPHY AND LAYERED STRUCTURES FORMED THEREFROM | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |