SCHEMBL20165516

SCHEMBL20165516

CCOC(=O)CC(c1ccccc1)N(CC(C)C)C(=O)OCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
LMNA P02545 1/20 0.46
POLB P06746 1/20 0.46
HSD17B10 Q99714 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CHRNB2 P17787 1/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
CHRNA4 P43681 1/20 0.43
TSHR P16473 1/20 0.42
F2 P00734 1/20 0.40
MAPT P10636 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
MMP8 P22894 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
F10 P00742 1/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28485971 0.91 ALDH1A1 (0.47) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL20165515 0.88 ALDH1A1 (0.49) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL20166108 0.85 ALDH1A1 (0.47) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL11990750 0.82 CHRNB2 (0.54) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL24661643 0.81 ALDH1A1 (0.50) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL20165985 0.81 CHRNB2 (0.47) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL20165410 0.78 SMN1; SMN2 (0.46) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL28481792 0.78 LMNA (0.50) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL21522832 0.77 ALDH1A1 (0.43) ALDH1A1LMNAPOLBHSD17B10L3MBTL1
SCHEMBL28486670 0.76 ALDH1A1 (0.48) ALDH1A1LMNAPOLBHSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3541857-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2020-09-09 EP disclosed
US-10654946-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2020-05-19 US disclosed
US-20190330388-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2019-10-31 US disclosed
EP-3541857-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2019-09-25 EP disclosed
WO-2018091375-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-05-24 WO disclosed