Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenanthroline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 known ✓ | P22894 | 1/20 | 0.73 |
| ▸ | MMP13 known ✓ | P45452 | 1/20 | 0.73 |
| ▸ | CCR1 | P32246 | 4/20 | 0.73 |
| ▸ | CCR8 | P51685 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 4/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | CCR5 | P51681 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.73 |
| ▸ | MMP2 | P08253 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | GMNN | O75496 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | MMP9 | P14780 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenanthroline SCHEMBL27878282 | 0.98 | CCR1 (0.70) | CCR1CCR8LMNAKDM4ECCR5 | |
| Phenanthroline SCHEMBL23724038 | 0.96 | CCR1 (0.67) | CCR1CCR8LMNAKDM4ECCR5 | |
| Phenanthroline SCHEMBL9343811 | 0.88 | KDM4E (0.84) | CCR1CCR8LMNAKDM4ECCR5 | |
| Phenanthroline SCHEMBL23925464 | 0.86 | LMNA (0.73) | CCR1CCR8LMNAKDM4ECCR5 | |
| Phenanthroline SCHEMBL27878295 | 0.86 | KDM4E (0.80) | CCR1CCR8LMNAKDM4ECCR5 | |
| Phenanthroline SCHEMBL29367277 | 0.85 | CCR1 (1.00) | CCR1CCR8LMNAKDM4ECCR5 | |
| Phenanthroline SCHEMBL8845760 | 0.85 | CCR1 (1.00) | CCR1CCR8LMNAKDM4ECCR5 | |
| Phenanthroline SCHEMBL29354015 | 0.85 | CCR1 (1.00) | CCR1CCR8LMNAKDM4ECCR5 | |
| Phenanthroline SCHEMBL8312 | 0.85 | CCR1 (1.00) | CCR1CCR8LMNAKDM4ECCR5 | |
| Oxyquinoline SCHEMBL3211964 | 0.84 | TSHR (0.81) | CCR1CCR8LMNAKDM4ECCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119246450-B | Chemical determination device and method for iron content of silicon-aluminum alloy | 内蒙古汇能硅铝新材料科技有限公司 | 2025-03-04 | — | — | CN | claimed |
| CN-119246450-A | Chemical determination device and method for iron content of silicon-aluminum alloy | 内蒙古汇能硅铝新材料科技有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-118637615-A | Preparation method and application of hydrophilic integral foam carbon | 大连理工大学 | 2024-09-13 | — | — | CN | claimed |
| CN-113903934-B | Preparation method and application of porous Pd-PdO nanorods | 先进能源产业研究院(广州)有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-115089630-B | Ultrasonic coupling DESs extraction process for tuber fleeceflower stem polyphenols | 江苏大学 | 2023-11-03 | — | — | CN | claimed |
| CN-111282570-B | Preparation method and application of europium terbium exchanged birnessite type layered manganese oxide supported palladium catalyst | 北京工业大学 | 2023-02-03 | — | — | CN | claimed |
| CN-114464823-A | Oxygen reduction reaction catalyst and preparation method thereof | 先进能源产业研究院(广州)有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-113903934-A | Preparation method and application of porous Pd-PdO nanorod | 先进能源产业研究院(广州)有限公司 | 2022-01-07 | — | — | CN | claimed |
| CN-108478811-B | High-performance photo-thermal diagnosis and treatment integrated nano-particles and preparation method thereof | 湖北大学 | 2021-11-30 | — | — | CN | claimed |
| CN-110804052-B | Method for synthesizing and preparing 3,3 ', 5,5 ' -tetraalkyl-4, 4 ' -diphenoquinone | 山东师范大学 | 2021-07-20 | — | — | CN | claimed |
| CN-111777630-A | Rare earth terbium (III) complex and preparation method and application thereof | 衡阳师范学院 | 2020-10-16 | — | — | CN | claimed |
| CN-111282570-A | Preparation method and application of europium terbium exchanged birnessite type layered manganese oxide supported palladium catalyst | 北京工业大学 | 2020-06-16 | — | — | CN | claimed |
| CN-110804052-A | Method for synthesizing and preparing 3,3 ', 5,5 ' -tetraalkyl-4, 4 ' -diphenoquinone | 山东师范大学 | 2020-02-18 | — | — | CN | claimed |
| CN-110387593-A | A kind of preparation method of nanoscale bonding type Fluorescent falsification-preventing fiber | 太原理工大学 | 2019-10-29 | — | — | CN | claimed |
| CN-104650124-A | Preparation method of rare earth/acylpyrazolone/o-phenanthroline ternary complex | FU QIANG | 2015-05-27 | — | — | CN | claimed |
| CN-116190810-B | Aqueous solution sodium ion battery | 武汉浩元新能源有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-119633063-A | Preparation method and application of mint probiotic composition with halitosis preventing and/or relieving effects | 湖南协和健康科技研究院有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-101544991-A | Natural antioxidant of perilla flavone for cigarette and method for preparing same | CHINA TOBACCO HUBEI IND LLC | 2009-09-30 | — | — | CN | disclosed |
| CN-101214453-A | Catalyst and use thereof | HEFEI TEACHERS COLLEGE (CN) | 2008-07-09 | — | — | CN | disclosed |
| CN-100355857-C | Preparation method of organic electro luminous material rare earth europium organic metal complex | UNIV TAIYUAN TECHNOLOGY (CN) | 2007-12-19 | — | — | CN | disclosed |