SCHEMBL20165765

SCHEMBL20165765

OCCCC(C(F)(F)F)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1646882 0.84
SCHEMBL31474906 0.82
SCHEMBL21945778 0.80
SCHEMBL11522292 0.79
SCHEMBL11519475 0.79
SCHEMBL338407 0.75 SMN1; SMN2 (0.33) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL775155 0.75 SMN1; SMN2 (0.33) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL79029 0.73
SCHEMBL4023703 0.73 SMN1; SMN2 (0.37) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL1760755 0.73 SMN1; SMN2 (0.32) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110177798-B Catalyst and process for preparing same 博里利斯股份公司 2022-08-30 CN disclosed
US-11352376-B2 Catalysts BOREALIS AG (AT) 2022-06-07 US disclosed
EP-3541823-B1 CATALYSTS BOREALIS AG (AT) 2020-12-30 EP disclosed
US-20190308995-A1 CATALYSTS BOREALIS AG (AT) 2019-10-10 US disclosed
EP-3541823-A1 CATALYSTS Borealis AG (AT) 2019-09-25 EP disclosed
WO-2018091653-A1 CATALYST BOREALIS AG (AT) 2018-05-24 WO disclosed
WO-2018091684-A1 CATALYSTS BOREALIS AG (AT) 2018-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352376-B2 Catalysts SIGMAR1, H1-2, SFN SMN1; SMN2 3593/4885LMNA 3915/4885ALDH1A1 2139/4885
US-20190308995-A1 CATALYSTS SIGMAR1, H1-2, CBR1 SMN1; SMN2 3745/4885LMNA 3944/4885ALDH1A1 2045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.