SCHEMBL338407

SCHEMBL338407

OCCCC(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL864384 0.97 SMN1; SMN2 (0.32) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL6852245 0.94 LMNA (0.35) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL8671685 0.94 LMNA (0.35) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL6849263 0.94 LMNA (0.35) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL2637189 0.94 LMNA (0.35) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL879892 0.94 LMNA (0.35) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL2780201 0.85
SCHEMBL2929810 0.83 ATR (0.39)
SCHEMBL2348807 0.83 ESR1 (0.35)
SCHEMBL866197 0.82 SMN1; SMN2 (0.30) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 653 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079776-A Method for synthesizing fulvestrant intermediate by utilizing pentafluoroethane photocatalysis and application thereof 2026-05-26 CN claimed
EP-3947413-B1 PROCESS FOR PURIFYING LIRAGLUTIDE SCINOPHARM TAIWAN LTD (TW) 2026-02-18 EP claimed
US-12269844-B2 Process for purifying semaglutide and liraglutide SCINOPHARM TAIWAN, LTD. (TW) 2025-04-08 US claimed
CN-119431482-A Method for preparing fulvestrant intermediate N-3 by one-pot method 江西君业生物制药有限公司 2025-02-14 CN claimed
WO-2024258458-A1 HALOGENATED OLEFIN-CONTAINING POLYURETHANE FOAM-FORMING COMPOSITIONS, RELATED FOAMS AND METHODS FOR THEIR PRODUCTION COVESTRO LLC (US) 2024-12-19 WO claimed
CN-119031746-A Composite material and preparation method thereof, photoelectric device and preparation method thereof, and display device 广东聚华新型显示研究院 2024-11-26 CN claimed
CN-118930598-A Fulvestrant Process for the preparation of intermediates 杭州莱尼科技有限公司 2024-11-12 CN claimed
CN-114685593-B Fulvestrant preparation method and fulvestrant intermediate 鲁南制药集团股份有限公司 2024-01-23 CN claimed
CN-116003500-A Crystal form of fulvestrant intermediate and preparation method and application thereof 杭州九源基因工程有限公司 2023-04-25 CN claimed
US-11459354-B2 Process for purifying liraglutide SCINOPHARM TAIWAN, LTD. (TW) 2022-10-04 US claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
EP-0909749-B1 Process for the preparation of pentafluoropentanol BAYER AG (DE) 2002-08-28 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
EP-1027351-A1 PHENANTHROLINE DERIVATIVES FIBROGEN, INC. (US) 2000-08-16 EP claimed
US-6002053-A Process for preparing pentafluoropentanol BAYER AKTIENGESELLSCHAFT (DE) 1999-12-14 US claimed
WO-1999021860-B1 PHENANTHROLINE DERIVATIVES FIBROGEN INC (US) 1999-08-05 WO claimed
US-5916898-A ANTIFIBROPROLIFERTIVE, ENZYME INHIBITORS OF PYROLYL 4-HYDROXYLASE, ANTIARTHRITIC AGENTS ZENECA LIMITED (GB) 1999-06-29 US claimed
WO-1999021860-A1 PHENANTHROLINE DERIVATIVES FIBROGEN, INC. (US) 1999-05-06 WO claimed
EP-0909749-A1 Process for the preparation of pentafluoropentanol BAYER AG (DE) 1999-04-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11459354-B2 Process for purifying liraglutide GLP1R, GCG, IAPP SMN1; SMN2 3282/4885LMNA 3743/4885ALDH1A1 3453/4885
US-12269844-B2 Process for purifying semaglutide and liraglutide GLP1R, GCG, DPP4 SMN1; SMN2 2956/4885LMNA 4064/4885ALDH1A1 1296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.