Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20165830 | 0.83 | KMT2A (0.46) | HTTKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8513944 | 0.80 | MAPT (0.55) | HTTKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL12426042 | 0.76 | HTT (0.82) | HTTKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL358946 | 0.75 | HTT (0.61) | HTTKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL31171019 | 0.75 | HTT (0.61) | HTTKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL2337052 | 0.75 | KMT2A (0.67) | HTTKMT2AMEN1MAPTLMNA | |
| SCHEMBL10790188 | 0.73 | HTT (0.68) | HTTKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL27796244 | 0.73 | SLC9A1 (0.56) | HTTKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL4548035 | 0.73 | EPHX1 (0.70) | HTTKMT2AMEN1MAPTLMNA | |
| SCHEMBL20535978 | 0.72 | TSHR (0.47) | HTTKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091978-A1 | A PROCESS FOR THE PREPARATION OF 2-NITRO-4,5- DICHLOROACETANILIDE | AMOGH CHEMICALS PVT. LTD (IN) | 2018-05-24 | — | — | WO | disclosed |