SCHEMBL20165895

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL820505	0.86	ESR2 (0.48)	SQORCYP2C19KDM4EHPGDTSHR
	SCHEMBL31663604	0.83	ADORA1 (0.56)	HTTSQORCYP2C19KDM4ETSHR
	SCHEMBL30359283	0.82	SMN1; SMN2 (0.51)	SQORCYP2C19KDM4EHPGDTSHR
	SCHEMBL769515	0.82	SMN1; SMN2 (0.51)	SQORCYP2C19KDM4EHPGDTSHR
	SCHEMBL3224025	0.82	ESR2 (0.60)	GSK3AGSK3BHTTSQORCYP2C19
	SCHEMBL31663514	0.82	ESR2 (0.60)	GSK3AGSK3BHTTSQORCYP2C19
	Methane SCHEMBL28932814	0.81	SMN1; SMN2 (0.50)	SQORCYP2C19KDM4EHPGDTSHR
	SCHEMBL28721464	0.81	KDM4E (0.50)	HTTKDM4ELMNAHPGDTSHR
	SCHEMBL1423587	0.80	ESR2 (0.49)	GSK3AGSK3BHTTCYP2C19PDE3B
	SCHEMBL2657692	0.80	HTT (0.42)	GSK3AGSK3BHTTSQORCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.