Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20166074 | 0.92 | SMN1; SMN2 (0.39) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28481799 | 0.82 | TSHR (0.36) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5980962 | 0.80 | TSHR (0.40) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20165444 | 0.80 | TSHR (0.40) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21522944 | 0.79 | CYP2D6 (0.37) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28903531 | 0.79 | L3MBTL1 (0.36) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20166090 | 0.76 | MEN1 (0.42) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28488980 | 0.76 | ALDH1A1 (0.35) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4767066 | 0.75 | TSHR (0.37) | TSHRALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7286728 | 0.75 | TSHR (0.37) | TSHRALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541857-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018091375-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | WO | disclosed |