Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.49 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRB2 | P62993 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 4/20 | 0.38 |
| ▸ | KCNK10 | P57789 | 3/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | GIPR | P48546 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20166238 | 1.00 | PTPRZ1 (0.49) | PTPRZ1KDM6BPTPN1EPHX2NR1H4 | |
| SCHEMBL20166265 | 0.82 | GRB2 (0.60) | PTPRZ1PTPN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL12439873 | 0.82 | GRB2 (0.60) | PTPRZ1PTPN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL29771361 | 0.80 | PTPRZ1 (0.46) | PTPRZ1PTPN1ALDH1A1TDP1KCNK2 | |
| SCHEMBL10891346 | 0.80 | KDM6B (0.67) | KDM6B | |
| SCHEMBL18248013 | 0.77 | PPARG (0.53) | KDM6BPTPN1EPHX2GRB2 | |
| SCHEMBL10170597 | 0.77 | PPARG (0.53) | KDM6BPTPN1EPHX2GRB2 | |
| SCHEMBL963353 | 0.75 | PTPRZ1 (0.63) | PTPRZ1PTPN1EPHX2NR1H4ALDH1A1 | |
| SCHEMBL18247995 | 0.75 | PTPN1 (0.55) | KDM6BPTPN1EPHX2NR1H4GCGR | |
| SCHEMBL20586417 | 0.75 | PTPN1 (0.55) | KDM6BPTPN1EPHX2NR1H4GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11382949-B2 | Anthelmintic depsipeptide compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2022-07-12 | — | — | US | disclosed |
| US-20190307838-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-10-10 | — | — | US | disclosed |
| EP-3541789-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| CN-110167921-A | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | 勃林格殷格翰动物保健美国公司 | 2019-08-23 | — | — | CN | disclosed |
| WO-2018093920-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | MERIAL, INC. (US) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11382949-B2 | Anthelmintic depsipeptide compounds | ENPP2, ROCK2, RRP12 | PTPRZ1 1876/4885KDM6B 2032/4885PTPN1 849/4885 |
| US-20190307838-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | ENPP2, ROCK2, RRP12 | PTPRZ1 1876/4885KDM6B 2032/4885PTPN1 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.