Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.60 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | TPH1 | P17752 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20166265 | 1.00 | GRB2 (0.60) | GRB2SLC7A5PTPN1PTGS1ALPI | |
| SCHEMBL20166238 | 0.82 | PTPRZ1 (0.49) | GRB2PTPN1KDM4ETDP1PTPRZ1 | |
| SCHEMBL20166236 | 0.82 | PTPRZ1 (0.49) | GRB2PTPN1KDM4ETDP1PTPRZ1 | |
| SCHEMBL12673222 | 0.81 | SLC7A5 (0.67) | GRB2SLC7A5PTPN1PTGS1ALPI | |
| SCHEMBL2310526 | 0.80 | SLC7A5 (0.83) | GRB2SLC7A5PTPN1PTGS1ALPI | |
| SCHEMBL28320242 | 0.80 | SLC6A4 (0.43) | GRB2SLC7A5PTPN1KDM4ETDP1 | |
| SCHEMBL21447956 | 0.80 | SLC6A4 (0.43) | GRB2SLC7A5PTPN1KDM4ETDP1 | |
| SCHEMBL13957614 | 0.79 | SLC7A5 (0.59) | GRB2SLC7A5PTPN1PTGS1ALPI | |
| SCHEMBL26733282 | 0.78 | PTPN1 (0.65) | GRB2SLC7A5PTPN1PTGS1ALPI | |
| SCHEMBL43861 | 0.78 | GRB2 (0.76) | GRB2SLC7A5PTPN1PTGS1ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11382949-B2 | Anthelmintic depsipeptide compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2022-07-12 | — | — | US | disclosed |
| US-20190307838-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-10-10 | — | — | US | disclosed |
| EP-3541789-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| CN-110167921-A | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | 勃林格殷格翰动物保健美国公司 | 2019-08-23 | — | — | CN | disclosed |
| WO-2018093920-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | MERIAL, INC. (US) | 2018-05-24 | — | — | WO | disclosed |
| US-9199914-B2 | Multiple substituted fluoromethanes as selective and bioactive isosteres | MEH ASSOCIATES, INC. (US) | 2015-12-01 | — | — | US | disclosed |
| US-9199914-B2 | Multiple substituted fluoromethanes as selective and bioactive isosteres | MEH ASSOCIATES, INC. (US) | 2015-12-01 | — | — | US | disclosed |
| US-20120302519-A1 | MULTIPLE SUBSTITUTED FLUOROMETHANES AS SELECTIVE AND BIOACTIVE ISOSTERES | MEH ASSOCIATES, INC. (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120302519-A1 | MULTIPLE SUBSTITUTED FLUOROMETHANES AS SELECTIVE AND BIOACTIVE ISOSTERES | MEH ASSOCIATES, INC. (US) | 2012-11-29 | — | — | US | disclosed |
| WO-2011097421-A1 | MULTIPLE SUBSTITUTED FLUOROMETHANES AS SELECTIVE AND BIOACTIVE ISOSTERES | MEH ASSOCIATES, INC (US) | 2011-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11382949-B2 | Anthelmintic depsipeptide compounds | ENPP2, ROCK2, RRP12 | GRB2 2734/4885SLC7A5 4843/4885PTPN1 849/4885 |
| US-20120302519-A1 | MULTIPLE SUBSTITUTED FLUOROMETHANES AS SELECTIVE AND BIOACTIVE ISOSTERES | F2R, FDPS, MRGPRX2 | GRB2 589/4885SLC7A5 3913/4885PTPN1 2096/4885 |
| US-20190307838-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | ENPP2, ROCK2, RRP12 | GRB2 2734/4885SLC7A5 4843/4885PTPN1 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.