Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822736 | 0.93 | PTGDR2 (0.43) | MGLLPTGDR2FFAR1KDM4EUSP2 | |
| SCHEMBL20137041 | 0.84 | RXRA (0.38) | MGLLPTGDR2KDM4EUSP2ALDH1A1 | |
| SCHEMBL953869 | 0.82 | PTGDR2 (0.48) | PTGDR2ALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL22090766 | 0.81 | KDM4E (0.45) | TSHRPTGDR2KDM4EUSP2ALDH1A1 | |
| SCHEMBL8156747 | 0.81 | LTB4R (0.50) | MGLLTSHRPTGDR2FFAR1LTB4R | |
| SCHEMBL955509 | 0.80 | CYP1A1 (0.46) | PTGDR2KDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL31136545 | 0.80 | ALDH1A1 (0.42) | PTGDR2KDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL30924877 | 0.79 | TSHR (0.51) | TSHRPTGDR2FFAR1KDM4EALDH1A1 | |
| SCHEMBL30924879 | 0.79 | TSHR (0.51) | TSHRPTGDR2FFAR1KDM4EALDH1A1 | |
| SCHEMBL21722870 | 0.78 | APP (0.46) | PTGDR2KDM4EUSP2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541821-A1 | MAGL INHIBITORS | Abide Therapeutics, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| EP-3541820-A1 | MAGL INHIBITORS | Abide Therapeutics, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093947-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |
| WO-2018093949-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |