Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958557 | 0.89 | MEN1 (0.52) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8958237 | 0.89 | MEN1 (0.52) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9447837 | 0.89 | MEN1 (0.52) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL18173574 | 0.89 | MEN1 (0.52) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8958401 | 0.89 | MEN1 (0.52) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8958406 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL23636435 | 0.84 | MEN1 (0.50) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL17144002 | 0.84 | MEN1 (0.50) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| Triethylene Glycol SCHEMBL9447836 | 0.84 | MEN1 (0.50) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL22022676 | 0.84 | MEN1 (0.50) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541431-B1 | MYELOPEROXIDASE IMAGING AGENTS | MASSACHUSETTS GEN HOSPITAL (US) | 2024-04-17 | — | — | EP | disclosed |
| US-11352326-B2 | Myeloperoxidase imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2022-06-07 | — | — | US | disclosed |
| US-20190315689-A1 | Myeloperoxidase Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2019-10-17 | — | — | US | disclosed |
| EP-3541431-A1 | MYELOPEROXIDASE IMAGING AGENTS | The General Hospital Corporation (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018094005-A1 | MYELOPEROXIDASE IMAGING AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315689-A1 | Myeloperoxidase Imaging Agents | MPO, CAT, EPX | SMN1; SMN2 3674/4885MEN1 2886/4885KMT2A 3281/4885 |
| US-11352326-B2 | Myeloperoxidase imaging agents | MPO, CAT, EPX | SMN1; SMN2 3674/4885MEN1 2886/4885KMT2A 3281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.