Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 17/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168534 | 0.91 | MGLL (0.67) | MGLL | |
| SCHEMBL20168799 | 0.91 | MGLL (0.65) | MGLL | |
| SCHEMBL20168740 | 0.91 | MGLL (0.66) | MGLL | |
| SCHEMBL20137122 | 0.79 | MGLL (1.00) | MGLL | |
| SCHEMBL20168767 | 0.77 | MGLL (0.49) | MGLL | |
| SCHEMBL15094641 | 0.76 | MGLL (0.58) | MGLL | |
| SCHEMBL19974302 | 0.75 | MGLL (0.44) | MGLL | |
| SCHEMBL20168055 | 0.75 | MGLL (0.63) | MGLLALDH1A1KDM4E | |
| SCHEMBL19974451 | 0.74 | MGLL (0.53) | MGLL | |
| SCHEMBL23111753 | 0.73 | MGLL (0.41) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541821-A1 | MAGL INHIBITORS | Abide Therapeutics, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093947-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |