Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 20/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168799 | 0.86 | MGLL (0.65) | MGLLCYP2D6ABHD6 | |
| SCHEMBL23111753 | 0.85 | MGLL (0.41) | MGLLCYP2D6ABHD6 | |
| SCHEMBL20168796 | 0.81 | MGLL (0.41) | MGLLCYP2D6ABHD6 | |
| SCHEMBL28323581 | 0.80 | MGLL (0.53) | MGLLCYP2D6ABHD6 | |
| SCHEMBL15094641 | 0.79 | MGLL (0.58) | MGLLCYP2D6ABHD6 | |
| SCHEMBL20136929 | 0.78 | MGLL (0.79) | MGLLCYP2D6ABHD6 | |
| SCHEMBL20168515 | 0.77 | MGLL (0.65) | MGLL | |
| SCHEMBL20168534 | 0.77 | MGLL (0.67) | MGLLABHD6 | |
| SCHEMBL19974302 | 0.76 | MGLL (0.44) | MGLLCYP2D6ABHD6 | |
| SCHEMBL20168740 | 0.76 | MGLL (0.66) | MGLLABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541821-A1 | MAGL INHIBITORS | Abide Therapeutics, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093947-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |