Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168950 | 0.81 | HTR6 (0.51) | HTR6PDPK1IDO1MAOAMAOB | |
| SCHEMBL23686727 | 0.72 | HTR6 (0.44) | HTR6PDPK1IDO1MAOAMAOB | |
| SCHEMBL16242806 | 0.71 | HTR6 (0.57) | HTR6PDPK1IDO1MAOAMAOB | |
| SCHEMBL20962327 | 0.69 | HTR6 (0.34) | HTR6 | |
| SCHEMBL14393119 | 0.69 | HTR2A (0.35) | HTR6SIGMAR1ADRA2BADRA2CADRA1A | |
| SCHEMBL22932183 | 0.69 | BRD4 (0.36) | HTR6SIGMAR1ADRA2BADRA2CADRA1A | |
| SCHEMBL18676280 | 0.69 | HTR6 (0.39) | HTR6PDPK1IDO1SIGMAR1CYP11B2 | |
| SCHEMBL21370023 | 0.67 | HTR6 (0.45) | HTR6PDPK1IDO1MAOAMAOB | |
| SCHEMBL21369982 | 0.66 | HTR6 (0.44) | HTR6PDPK1IDO1MAOAMAOB | |
| SCHEMBL21302068 | 0.66 | KDM1A (0.42) | HTR6PDPK1MAOAMAOBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975972-B2 | Ethylene-based polymer, polyethylene-based resin composition and use thereof, catalyst component for olefin polymerization, olefin polymerization catalyst containing the component, and method for producing ethylene-based polymer by using the catalyst | JAPAN POLYETHYLENE CORPORATION (JP) | 2018-05-22 | — | — | US | disclosed |