Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23686727 | 0.86 | HTR6 (0.44) | HTR6PDPK1IDO1CA1CA2 | |
| SCHEMBL16242806 | 0.84 | HTR6 (0.57) | HTR6PDPK1IDO1CA1CA2 | |
| SCHEMBL20168951 | 0.81 | HTR6 (0.40) | HTR6PDPK1IDO1CA1CA2 | |
| SCHEMBL21370023 | 0.80 | HTR6 (0.45) | HTR6PDPK1IDO1CA1CA2 | |
| SCHEMBL21369982 | 0.78 | HTR6 (0.44) | HTR6PDPK1IDO1CA1CA2 | |
| SCHEMBL18676280 | 0.78 | HTR6 (0.39) | HTR6PDPK1IDO1CYP11B2SIGMAR1 | |
| SCHEMBL21302068 | 0.78 | KDM1A (0.42) | HTR6PDPK1MAOAMAOBCYP11B2 | |
| SCHEMBL22402756 | 0.76 | IDO1 (0.49) | HTR6PDPK1IDO1ADRA1A | |
| SCHEMBL2319101 | 0.76 | HTR6 (0.57) | HTR6PDPK1IDO1CA1CA2 | |
| SCHEMBL2026702 | 0.76 | HTR6 (0.57) | HTR6PDPK1IDO1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177619-A1 | Metallocene Catalyst Systems With Chemically-Treated Solid Oxides For Producing Ethylene-Based Plastomers And Elastomers | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2022-06-09 | — | — | US | disclosed |
| US-11014997-B2 | Dual catalyst system for producing high density polyethylenes with long chain branching | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2021-05-25 | — | — | US | disclosed |
| US-20210139619-A1 | Dual Catalyst System for Producing High Density Polyethylenes With Long Chain Branching | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2021-05-13 | — | — | US | disclosed |
| US-10975184-B2 | High-density ethylene-based polymer using hybrid supported metallocene catalyst and pipe using same | HANWHA CHEMICAL CORPORATION (KR) | 2021-04-13 | — | — | US | disclosed |
| US-10954321-B2 | High-density ethylene-based polymer using supported hybrid metallocene catalyst, and manufacturing method therefor | HANWHA CHEMICAL CORPORATION (KR) | 2021-03-23 | — | — | US | disclosed |
| US-20200362064-A1 | Dual Catalyst System for Producing High Density Polyethylenes With Long Chain Branching | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2020-11-19 | — | — | US | disclosed |
| US-20200190238-A1 | HIGH-DENSITY ETHYLENE-BASED POLYMER USING HYBRID SUPPORTED METALLOCENE CATALYST AND PIPE USING SAME | HANWHA CHEMICAL CORPORATION (KR) | 2020-06-18 | — | — | US | disclosed |
| US-20190169325-A1 | HIGH-DENSITY ETHYLENE-BASED POLYMER USING SUPPORTED HYBRID METALLOCENE CATALYST, AND MANUFACTURING METHOD THEREFOR | HANWHA CHEMICAL CORPORATION (KR) | 2019-06-06 | — | — | US | disclosed |
| US-9975972-B2 | Ethylene-based polymer, polyethylene-based resin composition and use thereof, catalyst component for olefin polymerization, olefin polymerization catalyst containing the component, and method for producing ethylene-based polymer by using the catalyst | JAPAN POLYETHYLENE CORPORATION (JP) | 2018-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10975184-B2 | High-density ethylene-based polymer using hybrid supported metallocene catalyst and pipe using same | EEF1E1, EPN1, EEF1A1 | HTR6 4250/4885PDPK1 1331/4885IDO1 4352/4885 |
| US-20200190238-A1 | HIGH-DENSITY ETHYLENE-BASED POLYMER USING HYBRID SUPPORTED METALLOCENE CATALYST AND PIPE USING SAME | EEF1E1, EPN1, EEF1A1 | HTR6 4250/4885PDPK1 1331/4885IDO1 4352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.