Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 17/20 | 0.65 |
| ▸ | CA2 | P00918 | 17/20 | 0.65 |
| ▸ | CA9 | Q16790 | 14/20 | 0.65 |
| ▸ | CA12 | O43570 | 13/20 | 0.61 |
| ▸ | CA7 | P43166 | 3/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14509390 | 0.83 | ALDH1A1 (0.53) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL25033056 | 0.81 | CA1 (0.57) | CA1CA2CA9CA12CA7 | |
| SCHEMBL13589509 | 0.81 | TDP1 (0.48) | CA1CA2CA9ALDH1A1 | |
| SCHEMBL24714992 | 0.81 | TDP1 (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL13588732 | 0.79 | TDP1 (0.46) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL8761539 | 0.79 | TDP1 (0.46) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL27485395 | 0.78 | CA2 (0.55) | CA1CA2CA9CA12CA7 | |
| SCHEMBL27327537 | 0.77 | CA1 (0.50) | CA1CA2CA9CA12CA7 | |
| SCHEMBL39430 | 0.76 | TDP1 (0.72) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL21104560 | 0.76 | CA2 (0.63) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061362-A | Preparation method of bentazon | JIANGSU TAICANG AGRICULTURAL CHEMICALS CO LTD | 2015-11-18 | — | — | CN | claimed |
| CN-117794924-A | Compounds useful as inhibitors of ATR kinase | 苏州爱科百发生物医药技术有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-11325905-B2 | Imidopiperidine compounds as inhibitors of human polynucleotide kinase phosphatase | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2022-05-10 | — | — | US | disclosed |
| US-20200148675-A1 | IMIDOPIPERIDINE COMPOUNDS AS INHIBITORS OF HUMAN POLYNUCLEOTIDE KINASE PHOSPHATASE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2020-05-14 | — | — | US | disclosed |
| US-9975905-B2 | Derivatized 3-styryl-cephalosporins | GLADIUS PHARMACEUTICALS CORPORATION (CA) | 2018-05-22 | — | — | US | disclosed |
| CN-105061362-A | Preparation method of bentazon | JIANGSU TAICANG AGRICULTURAL CHEMICALS CO LTD | 2015-11-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11325905-B2 | Imidopiperidine compounds as inhibitors of human polynucleotide kinase phosphatase | PNKP, PPM1A, PPM1B | CA1 4676/4885CA2 3139/4885CA9 4521/4885 |
| US-20200148675-A1 | IMIDOPIPERIDINE COMPOUNDS AS INHIBITORS OF HUMAN POLYNUCLEOTIDE KINASE PHOSPHATASE | PNKP, PPM1A, PPM1B | CA1 4676/4885CA2 3139/4885CA9 4521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.