SCHEMBL24714992

SCHEMBL24714992

CC(C)Nc1ccc(S(C)(C)N)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.48
ALDH1A1 P00352 4/20 0.47
CYP3A4 P08684 2/20 0.47
THRB P10828 2/20 0.47
ALOX15 P16050 2/20 0.47
TSHR P16473 2/20 0.47
HSD17B10 Q99714 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
LMNA P02545 2/20 0.47
ALOX12 P18054 1/20 0.47
RECQL P46063 1/20 0.47
ATM Q13315 1/20 0.47
CA1 P00915 14/20 0.45
CA2 P00918 14/20 0.45
CA9 Q16790 12/20 0.45
CA12 O43570 11/20 0.40
RXFP1 Q9HBX9 1/20 0.39
TP53 P04637 1/20 0.37
HSP90AA1 P07900 1/20 0.37
CASP1 P29466 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20169264 0.81 CA1 (0.65) ALDH1A1CA1CA2CA9CA12
SCHEMBL13589509 0.78 TDP1 (0.48) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL39430 0.78 TDP1 (0.72) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL14509390 0.76 ALDH1A1 (0.53) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL13588732 0.72 TDP1 (0.46) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL8761539 0.72 TDP1 (0.46) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL475453 0.72 TDP1 (0.56) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL22648282 0.72 TDP1 (0.56) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL9934007 0.71 TDP1 (0.81) TDP1ALDH1A1CYP3A4THRBALOX15
SCHEMBL8431367 0.70 TDP1 (0.54) TDP1ALDH1A1CYP3A4THRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022213193-A1 COMPOSITIONS AND METHODS FOR REMOVING BORON FROM AQUEOUS SOLUTIONS CARBONET NANOTECHNOLOGIES INC. (CA) 2022-10-13 WO disclosed