Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 12/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15282735 | 0.86 | DGAT1 (0.60) | DGAT1PTGS2PTGS1METAP2 | |
| SCHEMBL9940541 | 0.85 | DGAT1 (0.48) | DGAT1PTGS2PTGS1METAP2 | |
| SCHEMBL20169353 | 0.84 | DGAT1 (0.52) | DGAT1PTGS2PTGS1 | |
| SCHEMBL20169325 | 0.80 | DGAT1 (0.47) | DGAT1PTGS2PTGS1 | |
| SCHEMBL20169324 | 0.78 | DGAT1 (0.45) | DGAT1PTGS2PTGS1 | |
| SCHEMBL20169323 | 0.78 | DGAT1 (0.47) | DGAT1PTGS2PTGS1 | |
| SCHEMBL20169317 | 0.77 | DGAT1 (0.48) | DGAT1PTGS2PTGS1 | |
| SCHEMBL20169375 | 0.76 | DGAT1 (0.52) | DGAT1PTGS2PTGS1 | |
| SCHEMBL20169367 | 0.76 | DGAT1 (0.55) | DGAT1 | |
| SCHEMBL27348100 | 0.76 | DGAT1 (0.44) | DGAT1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975871-B2 | Continuous arycyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2018-05-22 | — | — | US | disclosed |