SCHEMBL2016950

SCHEMBL2016950

C=CCS(=O)(=O)S(=O)(=O)CC=C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7645284 0.81 TSHR (0.30)
SCHEMBL1870918 0.81
SCHEMBL27921339 0.81
SCHEMBL750132 0.81 CA2 (0.37) CA2CA9
SCHEMBL1865093 0.79
Diallylsulfone SCHEMBL9947 0.77
Sulfuric Acid SCHEMBL28016689 0.77
SCHEMBL2833432 0.76 CA1 (0.30) CA2
SCHEMBL2833435 0.76 CA1 (0.30) CA2
Diallylsulfone SCHEMBL17707262 0.74 CA2 (0.31) CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1689757-A4 HETEROCYCLIC BORONIC ACID COMPOUNDS PHENOMIX CORP (US) 2007-01-10 EP claimed
EP-1689757-A1 HETEROCYCLIC BORONIC ACID COMPOUNDS Phenomix Corporation (US) 2006-08-16 EP claimed
WO-2005047297-A1 HETEROCYCLIC BORONIC ACID COMPOUNDS PHENOMIX CORPORATION (US) 2005-05-26 WO claimed
US-4606862-A INSECTICIDE INTERMEDIATES SHELL OIL COMPANY (US) 1986-08-19 US claimed
US-4531002-A Process for preparing insecticidal N-acyl-tetrahydro-2-nitromethylene-2H-1,3-thiazines SHELL OIL COMPANY (US) 1985-07-23 US claimed
US-20240216350-A1 SEMI-SOLID TOPICAL COMPOSITION CONTAINING PIRFENIDONE AND MODIFIED DIALLYL DISULFIDE OXIDE (M-DDO) FOR ELIMINATING OR PREVENTING ACNE EXCALIBUR PHARMACEUTICALS, INC. (US) 2024-07-04 US disclosed
US-11766426-B2 Semi-solid topical composition containing pirfenidone and modified diallyl disulfide oxide (M-DDO) for eliminating or preventing acne EXCALIBUR PHARMACEUTICALS, INC. (US) 2023-09-26 US disclosed
US-20210346360-A1 SEMI-SOLID TOPICAL COMPOSITION CONTAINING PIRFENIDONE AND MODIFIED DIALLYL DISULFIDE OXIDE (M-DDO) FOR ELIMINATING OR PREVENTING ACNE EXCALIBUR PHARMACEUTICALS, INC. (US) 2021-11-11 US disclosed
US-11013727-B2 Semi-solid topical composition containing pirfenidone and modified diallyl disulfide oxide (M-DDO) for eliminating or preventing acne EXCALIBUR PHARMACEUTICALS, INC. (US) 2021-05-25 US disclosed
US-20200061040-A1 SEMI-SOLID TOPICAL COMPOSITION CONTAINING PIRFENIDONE AND MODIFIED DIALLYL DISULFIDE OXIDE (M-DDO) FOR ELIMINATING OR PREVENTING ACNE Cell Therapy and Technology S.A. DE C.V. (MX) 2020-02-27 US disclosed
US-20180214434-A1 SEMI-SOLID TOPICAL COMPOSITION CONTAINING PIRFENIDONE AND MODIFIED DIALLYL DISULFIDE OXIDE (M-DDO) FOR ELIMINATING OR PREVENTING ACNE EXCALIBUR PHARMACEUTICALS, INC. 2018-08-02 US disclosed
US-9949959-B2 Semi-solid topical composition containing pirfenidone and modified diallyl disulfide oxide (M-DDO) for eliminating or preventing acne Cell Therapy and Technology S.A. DE C.V. (MX) 2018-04-24 US disclosed
EP-2832354-A1 SEMI-SOLID TOPICAL COMPOSITION WHICH CONTAINS PIRFENIDONE AND MODIFIED DIALLYL DISULPHIDE OXIDE (M-DDO) FOR ELIMINATING OR PREVENTING ACNE Cell Therapy and Technology S.A. de C.V. (MX) 2015-02-04 EP disclosed
US-8221775-B2 Pyrrolin-2-ylamino compounds for combating animal pests BASF SE (DE) 2012-07-17 US disclosed
US-8211924-B2 1-(azolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests BASF SE (DE) 2012-07-03 US disclosed
US-20110160269-A1 Pyrrolin-2-ylamino Compounds For Combating Animal Pests BASF SE 2011-06-30 US disclosed
US-20100280078-A1 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests BASF SE (DE) 2010-11-04 US disclosed
US-20100167925-A1 Substituted Azolin-2-yl-Amino Compounds BASF SE (DE) 2010-07-01 US disclosed
US-20100010058-A1 Azoline Compounds for Combating Arthropod Pests BASF SE (DE) 2010-01-14 US disclosed
US-4487951-A INTERMEDIATES FOR PLANT GROWTH REGULATORS AND HERBICIDES CIBA-GEIGY CORPORATION (US) 1984-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216350-A1 SEMI-SOLID TOPICAL COMPOSITION CONTAINING PIRFENIDONE AND MODIFIED DIALLYL DISULFIDE OXIDE (M-DDO) FOR ELIMINATING OR PREVENTING ACNE DAO, DDO, CUTA CA2 4184/4885CA9 4398/4885
US-20210346360-A1 SEMI-SOLID TOPICAL COMPOSITION CONTAINING PIRFENIDONE AND MODIFIED DIALLYL DISULFIDE OXIDE (M-DDO) FOR ELIMINATING OR PREVENTING ACNE DAO, DDO, CUTA CA2 4184/4885CA9 4398/4885
US-20180214434-A1 SEMI-SOLID TOPICAL COMPOSITION CONTAINING PIRFENIDONE AND MODIFIED DIALLYL DISULFIDE OXIDE (M-DDO) FOR ELIMINATING OR PREVENTING ACNE DAO, DDO, CUTA CA2 4184/4885CA9 4398/4885
US-20110160269-A1 Pyrrolin-2-ylamino Compounds For Combating Animal Pests RXFP3, CBR3, ATL3 CA2 2769/4885CA9 4472/4885
US-20100167925-A1 Substituted Azolin-2-yl-Amino Compounds CBR3, NR2C2, HRH3 CA2 512/4885CA9 1934/4885
US-11766426-B2 Semi-solid topical composition containing pirfenidone and modified diallyl disulfide oxide (M-DDO) for eliminating or preventing acne DAO, DDO, CUTA CA2 4184/4885CA9 4398/4885
US-20100010058-A1 Azoline Compounds for Combating Arthropod Pests NR0B1, NR4A1, NR4A3 CA2 1049/4885CA9 916/4885
US-20200061040-A1 SEMI-SOLID TOPICAL COMPOSITION CONTAINING PIRFENIDONE AND MODIFIED DIALLYL DISULFIDE OXIDE (M-DDO) FOR ELIMINATING OR PREVENTING ACNE DAO, DDO, CUTA CA2 4184/4885CA9 4398/4885
US-11013727-B2 Semi-solid topical composition containing pirfenidone and modified diallyl disulfide oxide (M-DDO) for eliminating or preventing acne DAO, DDO, CUTA CA2 4184/4885CA9 4398/4885
US-20100280078-A1 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests NR0B1, NR0B2, NR2C2 CA2 1485/4885CA9 2542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.