SCHEMBL20169556

SCHEMBL20169556

BC(=O)CCN1C(=O)C=CC1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 8/20 0.52
FAAH O00519 4/20 0.52
PTGS1 P23219 7/20 0.52
PTGS2 P35354 7/20 0.52
ALDH1A1 P00352 3/20 0.50
LMNA P02545 2/20 0.50
MAPT P10636 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
HSP90AA1 P07900 2/20 0.50
HPGD P15428 2/20 0.50
TLR9 Q9NR96 1/20 0.50
TP53 P04637 1/20 0.50
PKM P14618 1/20 0.50
XBP1 P17861 1/20 0.50
MAPK1 P28482 1/20 0.50
HTT P42858 1/20 0.50
RECQL P46063 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
GPR35 Q9HC97 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29044909 0.84 MGLL (0.54) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL16405262 0.84 MGLL (0.54) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL23106270 0.84 PTGS1 (0.70) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL24342103 0.84 PTGS1 (0.70) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL34464 0.79 PTGS1 (0.70) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL15391717 0.79 PTGS1 (0.70) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL852360 0.77 MGLL (0.52) MGLLFAAHPTGS1PTGS2ALDH1A1
Hydrochloric Acid SCHEMBL25414956 0.77 PTGS1 (0.68) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL255340 0.77 MGLL (0.52) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL28981238 0.77 PTGS1 (0.68) MGLLFAAHPTGS1PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10987420-B2 Synthetic conjugate of CpG DNA and T-help/CTL peptide CITY OF HOPE (US) 2021-04-27 US disclosed
US-20200246455-A1 SYNTHETIC CONJUGATE OF CpG DNA AND T-HELP/CTL PEPTIDE CITY OF HOPE (US) 2020-08-06 US disclosed
US-10596254-B2 Synthetic conjugate of CpG DNA and T-help/CTL peptide CITY OF HOPE (US) 2020-03-24 US disclosed
US-9974854-B2 Synthetic conjugate of CpG DNA and T-help/CTL peptide CITY OF HOPE (US) 2018-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10596254-B2 Synthetic conjugate of CpG DNA and T-help/CTL peptide MICA, CD4, HLA-DRB1 MGLL 4742/4885FAAH 4080/4885PTGS1 3697/4885
US-10987420-B2 Synthetic conjugate of CpG DNA and T-help/CTL peptide MICA, CD4, HLA-DRB1 MGLL 4742/4885FAAH 4080/4885PTGS1 3697/4885
US-20200246455-A1 SYNTHETIC CONJUGATE OF CpG DNA AND T-HELP/CTL PEPTIDE MICA, CD4, HLA-DRB1 MGLL 4742/4885FAAH 4080/4885PTGS1 3697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.