SCHEMBL255340

SCHEMBL255340

NC(=O)CCN1C(=O)C=CC1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 7/20 0.52
FAAH O00519 3/20 0.52
PTGS1 P23219 7/20 0.52
PTGS2 P35354 7/20 0.52
ALDH1A1 P00352 3/20 0.50
LMNA P02545 2/20 0.50
MAPT P10636 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
HPGD P15428 2/20 0.50
HSP90AA1 P07900 1/20 0.50
TLR9 Q9NR96 1/20 0.50
TP53 P04637 1/20 0.50
PKM P14618 1/20 0.50
XBP1 P17861 1/20 0.50
MAPK1 P28482 1/20 0.50
HTT P42858 1/20 0.50
RECQL P46063 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
GPR35 Q9HC97 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL2193141 0.94 PTGS1 (0.47) MGLLFAAHPTGS1PTGS2ALDH1A1
Ethylene Glycol SCHEMBL1082278 0.94 PTGS1 (0.47) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL1704532 0.89 MGLL (0.62) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL31038302 0.88 PTGS1 (0.46) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL22398888 0.87 PTGS1 (0.69) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL14398036 0.86 PTGS1 (0.41) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL30180925 0.85 PTGS1 (0.72) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL28698933 0.85 PTGS1 (0.72) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL1887612 0.85 PTGS1 (0.72) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL19817136 0.85 PTGS1 (0.72) MGLLFAAHPTGS1PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 544 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113195487-A 2, 3-diaminosuccinyl conjugate linkers 杭州多禧生物科技有限公司 2021-07-30 CN claimed
US-10696699-B2 Charged linkers and their uses for conjugation HANGZHOU DAC BIOTECH CO., LTD. (CN) 2020-06-30 US claimed
US-10696700-B2 Charged linkers and their uses for conjugation HANGZHOU DAC BIOTECH CO., LTD. (CN) 2020-06-30 US claimed
US-10683314-B2 Charged linkers and their uses for conjugation HANGZHOU DAC BIOTECH CO., LTD. (CN) 2020-06-16 US claimed
US-10464955-B2 Charged linkers and their uses for conjugation HANGZHOU DAC BIOTECH CO., LTD. (CN) 2019-11-05 US claimed
US-20090317408-A1 LIGAND CONJUGATED THERMOTHERAPY SUSCEPTORS AND METHODS FOR PREPARING SAME ADURO BIOTECH (US) 2009-12-24 US claimed
EP-1648933-B1 LONG LASTING INSULIN DERIVATIVES AND METHODS THEREOF CONJUCHEM BIOTECHNOLOGIES INC (CA) 2009-06-17 EP claimed
EP-1322234-A2 RESORBABLE ANASTOMOSIS STENTS AND PLUGS Cohesion Technologies, Inc. (US) 2003-07-02 EP claimed
WO-2002024114-A2 RESORBABLE ANASTOMOSIS STENTS AND PLUGS COHESION TECHNOLOGIES, INC. (US) 2002-03-28 WO claimed
US-12558432-B2 Biocompatible polymeric drug carriers for delivering active agents CIS BIOPHARMA AG (CH) 2026-02-24 US disclosed
EP-3695408-B1 MEDICAL USE OF CDK4/6- AND CHECKPOINT-INHIBITORS IN PHASED COMBINATION, IN TREATMENT OF CANCER BROAD INST INC (US) 2026-01-21 EP disclosed
EP-3967649-B1 LIPID NANOPARTICLE UNIV HOKKAIDO NAT UNIV CORP (JP) 2025-11-12 EP disclosed
US-20250325588-A1 COMPOSITIONS AND METHODS FOR MAINTAINING A CCL3/CCL4 AND CCR5 INTERACTION PROGRAM EXPRESSED DURING TUMOR PROGRESSION THE BROAD INSTITUTE, INC. (US) 2025-10-23 US disclosed
EP-3237433-B1 METHOD OF PROTEIN MANUFACTURE UCB Biopharma SRL (BE) 2025-07-30 EP disclosed
WO-2003000647-A1 (ETHYLENE)-(PROPYLENE)-TRIAMINEPENTAACETIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE FOR THE PRODUCTION OF PHARMACEUTICAL AGENTS SCHERING AG (DE) 2003-01-03 WO disclosed
US-6414013-B1 KINASE INHIBITORS; ANTICANCER AGENTS PHARMACIA & UPJOHN S.P.A. (IT) 2002-07-02 US disclosed
WO-2001088160-A2 VECTORS FOR DNA DELIVERY ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI, S.P.A. (IT) 2001-11-22 WO disclosed
US-5879898-A DETECTION OF CD44 PROTEINS AND FOR THE IN VIVO IMAGING AND THERAPY OF TUMORS. ISIS INNOVATION LIMITED (GB) 1999-03-09 US disclosed
EP-0672130-A1 PEPTIDE CORRESPONDING TO CD44 EXON 6, ANTIBODIES SPECIFIC FOR SAID PEPTIDE AND USE OF THESE ANTIBODIES FOR DIAGNOSIS OF TUMORS ISIS INNOVATION LIMITED (GB) 1995-09-20 EP disclosed
WO-1994012631-A1 PEPTIDE CORRESPONDING TO CD44 EXON 6, ANTIBODIES SPECIFIC FOR SAID PEPTIDE AND USE OF THESE ANTIBODIES FOR DIAGNOSIS OF TUMORS ISIS INNOVATION LIMITED (GB) 1994-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558432-B2 Biocompatible polymeric drug carriers for delivering active agents MSR1, CD47, SLC43A1 MGLL 3798/4885FAAH 910/4885PTGS1 669/4885
US-10696700-B2 Charged linkers and their uses for conjugation PHOSPHO1, PCTP, CD2BP2 MGLL 3841/4885FAAH 2986/4885PTGS1 4717/4885
US-10464955-B2 Charged linkers and their uses for conjugation PHOSPHO1, PCTP, CD2BP2 MGLL 3841/4885FAAH 2986/4885PTGS1 4717/4885
US-10683314-B2 Charged linkers and their uses for conjugation PHOSPHO1, PCTP, CD2BP2 MGLL 3841/4885FAAH 2986/4885PTGS1 4717/4885
US-10696699-B2 Charged linkers and their uses for conjugation PHOSPHO1, PCTP, CD2BP2 MGLL 3841/4885FAAH 2986/4885PTGS1 4717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.